遗传修饰小鼠:修订间差异

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== '''国外一些转基因中心''' ==
在GB遗传修饰小鼠,也称作'''基因工程小鼠''',也叫遗传工程小鼠(Genetically Engineered Mouse Models),是指通过基因工程技术手段,对小鼠基因组进行一定的人为修饰,由此产生具有特定表型或特征的小鼠。 是研究基因功能、人类疾病的最主要的动物模型。


:*Johns Hopkins Univ. Transgenic Core Laboratory:[http://www.hopkinsmedicine.org/core/home.htm www.hopkinsmedicine.org/core/home.htm]
下面的资源只是列举了部分,不一定准确。欢迎大家讨论,修订。
:*U Wash. Transgenic Resources Program:https://www.washington.edu/research/shared-research-facilities-resources/transgenic-resources-program-trp/
 
:*U Penn. Transgenic & Chimeric Mouse Facility:https://genetics.med.upenn.edu/cores/tcmf
== 1. 国内 ==
:*Washington University Mouse Genetics Core:https://mousegeneticscore.wustl.edu/
=== 1.1 科研院所和高校建立 ===
:*University of Michigan Transgenic Animal Model Core:https://medresearch.umich.edu/office-research/about-office-research/biomedical-research-core-facilities/transgenic-animal-model
*清华大学实验动物中心:http://www.larc.tsinghua.edu.cn/category/AboutUs/Services
:*UCLA Cedars-Sinai Rodent Genetics Core:https://www.cedars-sinai.edu/research-education/research/cores/rodent-genetics.html
*北京大学实验动物中心:https://www.lac.pku.edu.cn/jzfw1/ptjzpt/index.htm
:*Duke University Transgenic Mouse Facility:http://www.tmf.cancer.duke.edu
*中科院动物所实验动物中心:http://lac.ioz.ac.cn/jsfw/jybjdwmxdz/crispr/
:*Yale University Animal Genomics Services:https://medicine.yale.edu/compmed/ags/
*苏州大学剑桥-苏大基因组资源中心(CAM-SU GRC):https://www.cam-su.cn
:*Stanford University Transgenic Mouse Research Facility:https://med.stanford.edu/tktc.html
 
:*University of Connecticut Gene Targeting and Transgenic Facility:https://health.uconn.edu/mouse-genome-modification/services
=== 1.2 常用公司 ===
:*UNC Chapel Hill Animal Model Core:https://www.med.unc.edu/corefacilities/core-listings-by-categories/animal-models/
*江苏集萃药康生物科技股份有限公司:https://www.gempharmatech.com
:*VCU Transgenic Mouse Core Facility:https://www.masseycancercenter.org/research/shared-resource-cores/transgenic-knock-out-mouse-shared-resource
*上海南方模式生物科技股份有限公司:[http://www.modelorg.com www.modelorg.com]
:*The Genetically Engineered Murine Model (GEMM) Core at UVA:https://med.virginia.edu/genetically-engineered-murine-model-core/
*赛业(广州)生物科技有限公司:https://www.cyagen.com/cn/zh-cn
 
== 2. 国外 ==
===2.1 资源整合和查询数据库 ===
*European Mouse Mutant Archive (EMMA): [http://www.infrafrontier.eu www.infrafrontier.eu]
*Mutant Mouse Regional Resource Centers (MMRRC):[http://www.mmrrc.org www.mmrrc.org]
*RIKEN:https://mus.brc.riken.jp/en
*International Mouse Strain Resource (IMSR):[http://www.findmice.org www.findmice.org]
*Knockout Mouse Project (KOMP): [http://www.knockoutmouse.org www.knockoutmouse.org]
 
=== 2.2 科研院所和高校建立 ===
*Johns Hopkins Univ. Transgenic Core Laboratory:[http://www.hopkinsmedicine.org/core/home.htm www.hopkinsmedicine.org/core/home.htm]
*U Wash. Transgenic Resources Program:https://www.washington.edu/research/shared-research-facilities-resources/transgenic-resources-program-trp/
*U Penn. Transgenic & Chimeric Mouse Facility:https://genetics.med.upenn.edu/cores/tcmf
*Washington University Mouse Genetics Core:https://mousegeneticscore.wustl.edu/
*University of Michigan Transgenic Animal Model Core:https://medresearch.umich.edu/office-research/about-office-research/biomedical-research-core-facilities/transgenic-animal-model
*UCLA Cedars-Sinai Rodent Genetics Core:https://www.cedars-sinai.edu/research-education/research/cores/rodent-genetics.html
*Duke University Transgenic Mouse Facility:http://www.tmf.cancer.duke.edu
*Yale University Animal Genomics Services:https://medicine.yale.edu/compmed/ags/
*Stanford University Transgenic Mouse Research Facility:https://med.stanford.edu/tktc.html
*University of Connecticut Gene Targeting and Transgenic Facility:https://health.uconn.edu/mouse-genome-modification/services
*UNC Chapel Hill Animal Model Core:https://www.med.unc.edu/corefacilities/core-listings-by-categories/animal-models/
*VCU Transgenic Mouse Core Facility:https://www.masseycancercenter.org/research/shared-resource-cores/transgenic-knock-out-mouse-shared-resource
*The Genetically Engineered Murine Model (GEMM) Core at UVA:https://med.virginia.edu/genetically-engineered-murine-model-core/
 
=== 2.3 常用公司 ===
*The Jackson Lab:https://www.jax.org
*Taconic:https://www.taconic.com
*Charles River Lab:https://www.criver.com
 
== '''3. [[Cre]]工具鼠查询''' ==
*上海南方模式:https://www.modelorg.com/findcre.html
*集萃药康:https://cn.gempharmatech.com/service/cre-dre.html 
*JAX:https://www.jax.org/research-and-faculty/resources/cre-repository

2024年7月28日 (日) 15:47的最新版本

在GB遗传修饰小鼠,也称作基因工程小鼠,也叫遗传工程小鼠(Genetically Engineered Mouse Models),是指通过基因工程技术手段,对小鼠基因组进行一定的人为修饰,由此产生具有特定表型或特征的小鼠。 是研究基因功能、人类疾病的最主要的动物模型。

下面的资源只是列举了部分,不一定准确。欢迎大家讨论,修订。

1. 国内

1.1 科研院所和高校建立

1.2 常用公司

2. 国外

2.1 资源整合和查询数据库

2.2 科研院所和高校建立

2.3 常用公司

3. Cre工具鼠查询