遗传修饰小鼠：修订间差异

2024年7月28日 (日) 11:43的版本

在GB遗传修饰小鼠，也称作基因工程小鼠，也叫遗传工程小鼠（Genetically Engineered Mouse Models），是指通过基因工程技术手段，对小鼠基因组进行一定的人为修饰，由此产生具有特定表型或特征的小鼠。是研究基因功能、人类疾病的最主要的动物模型。

科研院所和高校建立

国外内

清华大学实验动物中心：http://www.larc.tsinghua.edu.cn/category/AboutUs/Services
北京大学实验动物中心：https://www.lac.pku.edu.cn/jzfw1/ptjzpt/index.htm

国外

Johns Hopkins Univ. Transgenic Core Laboratory：www.hopkinsmedicine.org/core/home.htm
U Wash. Transgenic Resources Program：https://www.washington.edu/research/shared-research-facilities-resources/transgenic-resources-program-trp/
U Penn. Transgenic & Chimeric Mouse Facility：https://genetics.med.upenn.edu/cores/tcmf
Washington University Mouse Genetics Core：https://mousegeneticscore.wustl.edu/
University of Michigan Transgenic Animal Model Core：https://medresearch.umich.edu/office-research/about-office-research/biomedical-research-core-facilities/transgenic-animal-model
UCLA Cedars-Sinai Rodent Genetics Core：https://www.cedars-sinai.edu/research-education/research/cores/rodent-genetics.html
Duke University Transgenic Mouse Facility：http://www.tmf.cancer.duke.edu
Yale University Animal Genomics Services：https://medicine.yale.edu/compmed/ags/
Stanford University Transgenic Mouse Research Facility：https://med.stanford.edu/tktc.html
University of Connecticut Gene Targeting and Transgenic Facility：https://health.uconn.edu/mouse-genome-modification/services
UNC Chapel Hill Animal Model Core：https://www.med.unc.edu/corefacilities/core-listings-by-categories/animal-models/
VCU Transgenic Mouse Core Facility：https://www.masseycancercenter.org/research/shared-resource-cores/transgenic-knock-out-mouse-shared-resource
The Genetically Engineered Murine Model (GEMM) Core at UVA：https://med.virginia.edu/genetically-engineered-murine-model-core/

@@ 第1行： / 第1行： @@
-也称作'''基因工程小鼠'''，也叫遗传工程小鼠（Genetically Engineered Mouse Models），是指通过基因工程技术手段，对小鼠基因组进行一定的人为修饰，由此产生具有特定表型或特征的小鼠。 是研究基因功能、人类疾病的最主要的动物模型。
+在GB遗传修饰小鼠，也称作'''基因工程小鼠'''，也叫遗传工程小鼠（Genetically Engineered Mouse Models），是指通过基因工程技术手段，对小鼠基因组进行一定的人为修饰，由此产生具有特定表型或特征的小鼠。 是研究基因功能、人类疾病的最主要的动物模型。
-== '''国外一些转基因中心''' ==
+== 科研院所和高校建立 ==
+=== 国外内 ===
+*清华大学实验动物中心：http://www.larc.tsinghua.edu.cn/category/AboutUs/Services
+*北京大学实验动物中心：https://www.lac.pku.edu.cn/jzfw1/ptjzpt/index.htm
-:*Johns Hopkins Univ. Transgenic Core Laboratory：[http://www.hopkinsmedicine.org/core/home.htm www.hopkinsmedicine.org/core/home.htm]
+=== 国外 ===
-:*U Wash. Transgenic Resources Program：https://www.washington.edu/research/shared-research-facilities-resources/transgenic-resources-program-trp/
+*Johns Hopkins Univ. Transgenic Core Laboratory：[http://www.hopkinsmedicine.org/core/home.htm www.hopkinsmedicine.org/core/home.htm]
-:*U Penn. Transgenic & Chimeric Mouse Facility：https://genetics.med.upenn.edu/cores/tcmf
+*U Wash. Transgenic Resources Program：https://www.washington.edu/research/shared-research-facilities-resources/transgenic-resources-program-trp/
-:*Washington University Mouse Genetics Core：https://mousegeneticscore.wustl.edu/
+*U Penn. Transgenic & Chimeric Mouse Facility：https://genetics.med.upenn.edu/cores/tcmf
-:*University of Michigan Transgenic Animal Model Core：https://medresearch.umich.edu/office-research/about-office-research/biomedical-research-core-facilities/transgenic-animal-model
+*Washington University Mouse Genetics Core：https://mousegeneticscore.wustl.edu/
-:*UCLA Cedars-Sinai Rodent Genetics Core：https://www.cedars-sinai.edu/research-education/research/cores/rodent-genetics.html
+*University of Michigan Transgenic Animal Model Core：https://medresearch.umich.edu/office-research/about-office-research/biomedical-research-core-facilities/transgenic-animal-model
-:*Duke University Transgenic Mouse Facility：http://www.tmf.cancer.duke.edu
+*UCLA Cedars-Sinai Rodent Genetics Core：https://www.cedars-sinai.edu/research-education/research/cores/rodent-genetics.html
-:*Yale University Animal Genomics Services：https://medicine.yale.edu/compmed/ags/
+*Duke University Transgenic Mouse Facility：http://www.tmf.cancer.duke.edu
-:*Stanford University Transgenic Mouse Research Facility：https://med.stanford.edu/tktc.html
+*Yale University Animal Genomics Services：https://medicine.yale.edu/compmed/ags/
-:*University of Connecticut Gene Targeting and Transgenic Facility：https://health.uconn.edu/mouse-genome-modification/services
+*Stanford University Transgenic Mouse Research Facility：https://med.stanford.edu/tktc.html
-:*UNC Chapel Hill Animal Model Core：https://www.med.unc.edu/corefacilities/core-listings-by-categories/animal-models/
+*University of Connecticut Gene Targeting and Transgenic Facility：https://health.uconn.edu/mouse-genome-modification/services
-:*VCU Transgenic Mouse Core Facility：https://www.masseycancercenter.org/research/shared-resource-cores/transgenic-knock-out-mouse-shared-resource
+*UNC Chapel Hill Animal Model Core：https://www.med.unc.edu/corefacilities/core-listings-by-categories/animal-models/
-:*The Genetically Engineered Murine Model (GEMM) Core at UVA：https://med.virginia.edu/genetically-engineered-murine-model-core/
+*VCU Transgenic Mouse Core Facility：https://www.masseycancercenter.org/research/shared-resource-cores/transgenic-knock-out-mouse-shared-resource
+*The Genetically Engineered Murine Model (GEMM) Core at UVA：https://med.virginia.edu/genetically-engineered-murine-model-core/